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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3A1
All Species:
22.73
Human Site:
T541
Identified Species:
45.45
UniProt:
Q15459
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15459
NP_001005409.1
793
88886
T541
G
L
V
P
E
D
D
T
K
E
K
I
G
P
S
Chimpanzee
Pan troglodytes
XP_515067
793
88845
T541
G
L
V
P
E
D
D
T
K
E
K
I
G
P
S
Rhesus Macaque
Macaca mulatta
XP_001109090
793
88798
T541
G
L
V
P
E
D
D
T
K
E
K
I
G
P
S
Dog
Lupus familis
XP_534733
793
88764
T541
G
L
V
P
E
D
D
T
K
E
K
I
G
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Z5
791
88526
T539
G
L
V
P
E
D
D
T
K
E
K
I
G
P
S
Rat
Rattus norvegicus
NP_001100705
791
88569
T539
G
L
V
P
E
D
D
T
K
E
K
I
G
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026643
791
88489
D537
K
G
L
V
P
E
D
D
S
K
E
K
I
G
P
Frog
Xenopus laevis
NP_001085709
802
90334
G535
G
L
V
P
E
E
D
G
K
D
K
I
G
P
S
Zebra Danio
Brachydanio rerio
NP_956388
780
87898
D526
A
K
G
L
V
Q
E
D
D
S
K
E
K
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650583
784
88057
K550
G
L
L
P
D
E
E
K
E
K
I
G
P
K
P
Honey Bee
Apis mellifera
XP_393373
766
86238
E533
K
G
L
L
P
D
E
E
K
E
K
I
G
P
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXF1
785
87576
P560
P
I
V
R
P
L
P
P
P
P
N
L
A
L
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.6
98.6
N.A.
98.1
98.1
N.A.
N.A.
92.4
86.2
84.1
N.A.
52.4
58.1
N.A.
N.A.
Protein Similarity:
100
99.7
99.7
99.2
N.A.
98.3
98.4
N.A.
N.A.
95.4
92.3
91
N.A.
68
72.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
80
6.6
N.A.
20
46.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
33.3
93.3
13.3
N.A.
60
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
59
67
17
9
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
59
25
25
9
9
59
9
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
67
17
9
0
0
0
0
9
0
0
0
9
67
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
9
67
9
9
0
% I
% Lys:
17
9
0
0
0
0
0
9
67
17
75
9
9
9
9
% K
% Leu:
0
67
25
17
0
9
0
0
0
0
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% N
% Pro:
9
0
0
67
25
0
9
9
9
9
0
0
9
67
17
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
59
% S
% Thr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% T
% Val:
0
0
67
9
9
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _